The catabolite activator protein can overcome the effect of a repressor binding to the operon.

Question

Quizplus · Accepted Answer

The catabolite activator protein (CAP), when bound with cyclic AMP (cAMP), can facilitate transcription initiation by binding to a specific site on the DNA near the promoter of an operon, thereby enhancing RNA polymerase's ability to initiate transcription even in the presence of a repressor. This mechanism is part of the catabolite repression system, which allows bacteria to preferentially use certain sugars over others.

The Catabolite Activator Protein Can Overcome the Effect of a Repressor