Cytarabine Is a Nucleoside Analog Used as a Chemotherapeutic Agent

Cytarabine is a nucleoside analog used as a chemotherapeutic agent. Which of the following should be co-administered to limit chemically induced arachnoiditis on intrathecal injection?

A) Nothing. Chemically induced arachnoiditis does not occur with cytarabine use.
B) Dexamethasone should be co-administered to reduce arachnoiditis.
C) Nothing. Chemically induced arachnoiditis only occurs if the cytarabine is given too slowly. Otherwise, it is not a problem.
D) An OTC analgesic should be co-administered with the cytarabine to limit chemically induced arachnoiditis.