The mechanism of anesthetic action for lidocaine involves which of the following?

Question

Quizplus · Accepted Answer

The mechanism of anesthetic action for lidocaine involves blockade of axonal voltage-dependent sodium channels. Local anesthetic agents such as lidocaine inhibit nerve conduction through state- and use-dependent blockade of voltage-dependent fast sodium channels. As a result, the threshold of excitability of the nerve is increased and the ability of the nerve to propagate an action potential is decreased.

The Mechanism of Anesthetic Action for Lidocaine Involves Which of the Following