Capsules with bigger particles and intense packing have poor drug release and dissolution rate due to an increase in the pore size.

Question

Quizplus · Accepted Answer

Capsules with bigger particles and intense packing actually have a poor drug release and dissolution rate due to a decrease in the pore size, not an increase. Smaller pore sizes limit the penetration of the dissolution medium into the capsule, slowing down the release of the drug.

Capsules with Bigger Particles and Intense Packing Have Poor Drug