Which of the following is most likely to be associated with a high apparent volume of distribution
A) High hepatic extraction ratio
B) Penetration across the blood:brain and blood:testes barriers
C) Extensive binding to plasma protein
D) Extensive binding to tissue constituents
Correct Answer:
Verified
Q5: Which process involve alteration of drug distribution
A)Competitive
Q6: If drug have very small volume of
Q7: If distribution of drug is slower than
Q8: If the drug Y bind with plasma
Q9: The distribution of drugs into the central
Q11: The Initial distribution of drug into the
Q12: Transfer of drug from plasma to tissue
Q13: A hydrophilic medicinal agent has
A)Low ability to
Q14: Biological barriers include all except:
A)Renal tubules
B)Cell membranes
C)Capillary
Q15: Blood Brain Barrier is maximum permeable to
A)Na+
B)C02
C)Cl
D)K+
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