Conjugation of a drug includes the following except:

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Conjugation reactions in drug metabolism typically involve the addition of an endogenous substance to a functional group on the drug, thereby increasing its solubility and facilitating its excretion. Common conjugation reactions include glucuronidation, sulfate formation, and methylation. Hydrolysis, however, is not a conjugation reaction; it is a phase I metabolic reaction that involves the cleavage of molecules by the addition of water.

Conjugation of a Drug Includes the Following Except