What is the pathophysiological change in Parkinson's disease?
A) Degeneration of motor fibers in the pyramidal tracts
B) Excess secretion of stimulatory neurotransmitters in the CNS
C) Degeneration of the basal nuclei with a deficit of dopamine
D) Deficit of acetylcholine and degeneration of the motor cortex in the frontal lobe

Question

Quizplus · Accepted Answer

Parkinson's disease is characterized by the degeneration of the basal nuclei, particularly the substantia nigra, leading to a deficit of dopamine, which is crucial for regulating movement.

What Is the Pathophysiological Change in Parkinson's Disease