What is the primary reason for hypocalcemia developing during end-stage renal failure or uremia?
A) Decreased parathyroid hormone secretion
B) Insufficient calcium in the diet
C) Excessive excretion of calcium ions in the urine
D) A deficit of activated vitamin D and hyperphosphatemia

Question

Quizplus · Accepted Answer

In end-stage renal failure, the kidneys are unable to convert vitamin D to its active form, leading to decreased calcium absorption from the gut. Additionally, phosphate retention occurs, which binds calcium and further contributes to hypocalcemia.

What Is the Primary Reason for Hypocalcemia Developing During End-Stage