______________is produced by adipose tissue to signal fat storage reserves in the body, and mediates long-term appetitive controls,

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Leptin is a hormone produced by adipose (fat) tissue that signals the brain about the state of the body's fat reserves, playing a key role in regulating energy intake and expenditure, including appetite and metabolism. It helps mediate long-term appetite controls by indicating satiety, or fullness, to reduce food intake.

______________Is Produced by Adipose Tissue to Signal Fat Storage Reserves