Which statement about the direct antiglobulin test (DAT)in the postpartum period is true?

Question

Quizplus · Accepted Answer

If the mother has a clinically significant antibody, a DAT should be performed on a blood specimen from the newborn to determine if there is evidence of hemolysis. A positive DAT indicates the presence of bound IgG or complement on the newborn's red blood cells, which could lead to hemolysis. The other options are incorrect. A) Preparing and testing an eluate against the biological father's red blood cells would only be necessary if the newborn had a positive DAT and the mother did not have any identified antibodies. C) Laboratory standards do not mandate a DAT on every cord blood collected; it should only be performed if there is an indication based on maternal history or serologic testing. D) The strength of the DAT in ABO compatibility does not provide information about the severity of hemolysis, as ABO incompatibility typically results in mild hemolysis.

Which Statement About the Direct Antiglobulin Test (DAT)in the Postpartum