Which patients are at the highest risk for developing platelet refractoriness?

Question

Quizplus · Accepted Answer

Chronically transfused oncology patients are at the highest risk for developing platelet refractoriness, as they have received multiple transfusions which can lead to alloimmunization against platelet antigens. Anaesthetized surgical patients and multiparous obstetrical patients may also receive transfusions, but they are not typically chronically transfused and thus not as likely to develop platelet refractoriness. Bleeding trauma patients may require transfusions, but they are not at as high of a risk for developing platelet refractoriness as chronically transfused patients.

Which Patients Are at the Highest Risk for Developing Platelet