The secretion of gastrin by the pyloric antrum ceases:
A)When the stomach is distended by a full meal
B)When the gastric mucosa contents have a pH of about 2.0
C)If histamine is injected.
D)If the vagi are stimulated.

Question

Quizplus · Accepted Answer

Gastrin secretion by the pyloric antrum is inhibited when the pH of the gastric contents falls to about 2.0 or lower. This is a feedback mechanism to prevent excessive acidity in the stomach, which could damage the gastric mucosa.

The Secretion of Gastrin by the Pyloric Antrum Ceases