Which of the Following Correctly Represents the Pathophysiologic Mechanism Behind

Which of the following correctly represents the pathophysiologic mechanism behind development of cor pulmonale?

A) Pulmonary vasodilatation, compromise of vascular bed due to lung disease such as emphysema and interstitial lung disease, thinning of blood due to anticoagulants and primary pulmonary hypertension
B) Pulmonary vasoconstriction, compromise of vascular bed due to lung disease such as emphysema and interstitial lung disease, increased blood viscosity due to diseases like sickle cell anemia and primary pulmonary hypertension
C) Pulmonary vasodilatation, compromise of vascular bed due to lung disease such as emphysema and interstitial lung disease, valvular heart disease and primary pulmonary hypertension
D) Pulmonary vasoconstriction, compromise of vascular bed due to vascular diseases, increased blood viscosity due to diseases like sickle cell anemia and primary pulmonary hypertension