A 58-year-old man presents with weight loss and haemoptysis. He has smoked most of his life. On examination he is clubbed and has clinical evidence of right pleural effusion. His serum calcium is 3.2mM. Which of the following histological type of lung cancer is he most likely to suffer from?

Question

Quizplus · Accepted Answer

Squamous cell carcinoma of the lung is associated with hypercalcemia due to the production of parathyroid hormone-related peptide (PTHrP) by the tumor cells. This patient's presentation with weight loss, hemoptysis, a history of smoking, and hypercalcemia is suggestive of squamous cell carcinoma.

A 58-Year-Old Man Presents with Weight Loss and Haemoptysis