An Elderly Lady with Breast Cancer Is Starting Diamorphine Elixir

An elderly lady with breast cancer is starting diamorphine elixir for painful bony metastases. Which of the following is the most appropriate comment to make to her caregiver.

A) Sedation is likely to be an ongoing problem with diamorphine
B) If pain relief is not adequate cocaine may need to be introduced
C) A laxative will need to be used
D) Dependence on diamorphine is likely and could cause problems
E) The same dose could be given IM to achieve the same effect.