33- Which ONE of the Following Statements Regarding Colon Cancer

33- Which ONE of the following statements regarding colon cancer is correct:

A) In non-familial cases, gene mutations in the cancer cells are unusual
B) In familial cases the inheritance pattern is typically autosomal recessive
C) It occurs most commonly in the ascending colon
D) It is a characteristic feature of the Peutz-Jegher syndrome
E) In familial polyposis coli the increased cancer risk is due to inheritance of a mutated suppressor gene