Patient with Metastatic Bowel Cancer Is Taking Codeine 30 Mg

Patient with metastatic bowel cancer is taking Codeine 30 mg q4h without adequate analgesia. What is the most appropriate therapy?

A) continue Codeine and add Paracetamol 1g qid
B) stop Codeine, start MS Contain l0 mg bd and Paracetamol 1g qid
C) stop Codeine, start MS Contain 20 mg bd and Paracetamol 1g qid
D) stop Codeine, start MS Contain l0 mg bd and Panadeine ii qid
E) nerve block is now indicated