Which of the Following Statements About the Treatment of Bone

Which of the following statements about the treatment of bone metastases secondary to breast cancer is true?

A) Radiation therapy will achieve partial or complete pain relief within 4 weeks.
B) Single-fraction irradiation provides equivalent results to protracted radiation treatment schedules for pain control durability and reduced risk of subsequent fracture.
C) Metastatic sites with extraosseous bone involvement should be treated with 153Sm only, because localized external-beam irradiation is not beneficial.
D) An 8-Gy dose of hemibody irradiation should be administered in a single fraction to the upper, middle, or lower hemibody regions for treatment of painful bony metastases.