Closure of PDA may be achieved by medication or by surgical closure of the ductus.

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PDA results when the ductus fails to functionally close. During normal fetal circulation, the patent ductus short-circuits shunting the circulation from the lungs and instead directs blood from the pulmonary trunk to the aorta. If PDA continues after birth, circulation of oxygen is compromised because this abnormal opening is a shunt that allows oxygenated blood to recirculate through the lungs (see Figure 2-22). PDA is detected during a physical examination when a classic "machinery" murmur is heard on auscultation and palpitation reveals a thrill. The infant's growth and development may be slowed, and various signs of heart failure may be present. Closure may be attempted by drug therapy using an antiprostaglandin or ibuprofen. The other option is surgical closure of the ductus.

Closure of PDA May Be Achieved by Medication or by Surgical