Risk factors for primary bone tumors include

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The most affected bones are the pelvis, vertebrae, ribs, hip, femur, and humerus. Risk factors for primary bone tumors include prior chemotherapy, RT, or a history of Paget's disease or other benign bone lesions. Bone tumors, whether benign or malignant, are treated by surgical excision. The surrounding muscle, bone, and other tissue are often removed also, and bone grafting may be needed. The goal is to perform limb-sparing surgery, but tumor location and extent may necessitate amputation.

Risk Factors for Primary Bone Tumors Include