Agranulocytosis is usually caused by drug toxicity or hypersensitivity.

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Agranulocytosis is usually caused by drug toxicity or hypersensitivity. For example, cancer chemotherapy with chemotoxic agents can be a cause. Benzene is another chemical agent that causes neutropenia. Agranulocytosis, or neutropenia, is an acute insult to the body's immune system and drastically reduces the body's response to bacterial infection. The infectious agents usually invade the body through the oral or pharyngeal mucosa and are often already present but are no longer held in check by the now-absent granulocytes. Patients are occasionally sensitive to a particular drug, such as chlorpromazine, propylthiouracil, phenytoin, chloramphenicol, and phenylbutazone.

Agranulocytosis Is Usually Caused by Drug Toxicity or Hypersensitivity