Glomerulosclerosis describes renal changes that are due to a systemic endocrine disease and that are typical of
A) urethritis.
B) cystitis.
C) diabetic neuropathy.
D) polycystic kidney disease.

Question

Quizplus · Accepted Answer

Diabetic nephropathy refers to the renal changes resulting from diabetes mellitus, a systemic endocrine disease caused by failure of the pancreas to release enough insulin into the body (see "diabetes mellitus" section in Chapter 4). These changes, called glomerulosclerosis, can be expected eventually in all patients with insulin-dependent (type 1) diabetes, which increases their morbidity and mortality. Additionally, many patients with non-insulin-dependent (type 2) diabetes can also develop this kidney disorder. Diabetic glomerulosclerosis is a complication of diabetes mellitus; lesions of the glomeruli eventually cause the filtration rate to decrease. Insufficient control of blood glucose levels and blood pressure in the patient with diabetes may hasten the deterioration of renal function.

Glomerulosclerosis Describes Renal Changes That Are Due to a Systemic