People with Sickle-Cell Anemia Have Deformed Hemoglobin Molecules and Often

People with sickle-cell anemia have deformed hemoglobin molecules and often suffer muscle pains, even at low levels of exertion. These symptoms might come about because the deformed hemoglobin

A) is unable to carry the amount of oxygen required for normal activities of muscles.
B) cannot diffuse across the cells' membranes from the blood plasma.
C) causes damage to the muscle cells as it enters the muscle.
D) decreases the person's ratio of surface area to volume.