A nurse is reading an article about evidence-based practice and treatment of major depression. The nurse determines that the article provides the highest level of evidence. The evidence in the article would be based on:
A) Systematic review or meta-analysis of all relevant RCTs.
B) At least one well-designed RCT.
C) One well-designed nonrandom controlled trial.
D) Well-designed case-control and cohort studies.

Question

Quizplus · Accepted Answer

Systematic reviews or meta-analyses of all relevant randomized controlled trials (RCTs) are considered the highest level of evidence because they synthesize findings from multiple studies to provide a comprehensive overview of a particular topic or treatment efficacy.

A Nurse Is Reading an Article About Evidence-Based Practice and Treatment