The nurse is preparing to administer PRN medication to a client of a Japanese descent who is anxious. The prescription reads, Alprazolam (Xanax) 0.25 to 1.0 mg PO PRN. The best dose for the nurse to give initially is

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In general, nonwhites treated with Western dosing protocols have higher serum levels per dose and suffer more side effects. Persons of Asian descent often metabolize drugs more slowly, requiring lower doses to produce therapeutic effects.

The Nurse Is Preparing to Administer PRN Medication to a Client