A Patient with Parkinson Disease Is Considering Taking St

A patient with Parkinson disease is considering taking St.John's wort,an herbal remedy for depression,in addition to Sinemet and L-dopa.The best response is to make the patient aware that:

A) Depression is reduced by the use of herbal remedies such as St. John's wort.
B) Doses of St. John's wort and parkinsonian drugs should be taken on alternate days.
C) St. John's wort must be taken in large doses to reduce depression.
D) Herbal remedies can interfere with the effectiveness of the parkinsonian drugs.