Which of the Following Best Describes Enzymatic Activity

Which of the following best describes enzymatic activity?

A) Each enzyme has a preferred pH at which the enzyme reaction rate is highest.
B) Below a certain temperature, an enzyme will become denatured.
C) As the temperature increases, most enzymatic reactions will still proceed at the same rate.
D) Temperature has no impact on enzymatic activity.
E) Enzyme activity increases as substrate concentration decreases.