In cancer vaccines, macrophages that display tumor antigens are designed to

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In cancer vaccines, macrophages that display tumor antigens are designed to stimulate cytotoxic T cells to attack tumor cells. The process works as follows: macrophages, which are part of the immune system, can engulf and digest tumor cells or tumor antigens. They then present these antigens on their surface in a form that can be recognized by T cells. This antigen presentation is a crucial step in the activation of cytotoxic T cells, which are a subtype of T cells that can kill cancer cells.
Once activated, these cytotoxic T cells can seek out and destroy tumor cells throughout the body that display the same antigens. This immune response is part of the broader adaptive immune response, which can specifically target and remember the antigens of invaders, such as cancer cells. The goal of cancer vaccines is to train the immune system to recognize and combat cancer cells more effectively, thereby providing a therapeutic benefit to the patient.

In Cancer Vaccines, Macrophages That Display Tumor Antigens Are Designed