The intrauterine environment can have a profound and permanent effect on the developing fetus with or without chromosome or gene abnormalities.Most adverse intrauterine effects are the result of teratogens.The nurse is cognizant that this group of agents does not include:

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Amniotic bands are a congenital anomaly known as a "disruption" that occurs with the breakdown of previously normal tissue.Congenital amputations caused by amniotic bands are not the result of a teratogen.Other agents include Dilantin,warfarin,cytomegalovirus,radiation,and maternal PKU.

The Intrauterine Environment Can Have a Profound and Permanent Effect