The Nurse Administers Penicillin to a Client and Monitors the Client

The nurse administers penicillin to a client and monitors the client for an adverse reaction despite the client's denial of being allergic to penicillin. What is the rationale for checking for adverse reactions? Select all that apply.

A) A person can be allergic to any medication at any time.
B) Medications can react with over-the-counter medications to cause toxicity.
C) Certain medications react with orange juice to cause toxicity.
D) If medications are not taken on an empty stomach, adverse reactions may occur.
E) Medications can react with herbal supplements to cause adverse reactions.
F) Medications can react with other medications prescribed for the client.