A key step in the biosynthesis of glucose involves the reaction of glyceraldehyde 3-phosphate with dihydroxyacetone phosphate to form fructose 1,6-bisphosphate in the presence of an aldolase enzyme. The end product formed from this reaction is

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The reaction described leads to the formation of fructose 1,6-bisphosphate, which can exist in an equilibrium between its acyclic form and a cyclic hemiacetal form. This is due to the nature of the fructose molecule, which can cyclize to form a hemiacetal ring structure, but also exists in an open-chain (acyclic) form.

A Key Step in the Biosynthesis of Glucose Involves the Reaction