When researchers studied the extra chromosome 21, which is a hallmark of Down syndrome, on which gene did they find mutations?

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The APP gene, located on chromosome 21, has been linked to Down syndrome. Mutations in this gene are significant because they can lead to the production of amyloid precursor protein, which is involved in the formation of amyloid plaques found in the brains of people with Alzheimer's disease, a condition that individuals with Down syndrome are at an increased risk of developing as they age.

When Researchers Studied the Extra Chromosome 21, Which Is a Hallmark