In What Way Are Drugs and ESB Different from Natural

In what way are drugs and ESB different from natural rewards such as food, water, and sex?

A) Drugs and ESB have greater effects on dopamine in the mesolimbic pathway.
B) Drugs and ESB result in less dopamine increase in the nucleus accumbens than natural rewards do.
C) Drugs and ESB do not have rewarding effects through the mesolimbic pathway.
D) Animals are less likely to work to receive ESB or drugs than they are for natural rewards such as food.