Which Is the Best Choice to Place on a Reference

Which is the best choice to place on a reference list for a job application?

A) a professor you have a positive relationship with and who taught classes that have little connection to the position
B) a friend of your family you do not like but who works at a job similar to the position you are applying for
C) a professor you have a positive relationship with and who taught classes you attended that relate to the position
D) a relative you like, who has a prestigious job that has nothing to do with the position
E) a professor who is a leader in your field of interest but whom you never got along with