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Diabetes Mellitus Translates Roughly as "Copious Urination" + "Honey

Question 18

Multiple Choice

Diabetes mellitus translates roughly as "copious urination" + "honey." This disease results from disorders of glucose uptake by systemic cells and can cause, among other symptoms, high levels of glucose in the blood and glucose appearing in the urine (this is what diastix measure) . Which of the following is a reasonable explanation of this observation?


A) The reabsorption capacity of the kidney for glucose is exceeded.
B) A lack of sodium in the filtrate blocks the function of the Na+/glucose symport protein.
C) High levels of glucose interfere with ADH function.
D) The high levels of glucose induce a "dehydrated" state that promotes production of a large amount of dilute urine.
E) None of the choices given are a logical explanation for this observation.

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