Physical activity can produce reactive oxygen from an electron leak in the mitochondria, probably at the cytochrome level, which produces superoxide radicals.

Question

Quizplus · Accepted Answer

During physical activity, the increased demand for ATP leads to an enhanced electron flow through the mitochondrial electron transport chain. This can result in electron leakage, primarily at the level of complex I and III (often associated with the cytochrome components), leading to the partial reduction of oxygen to form superoxide radicals, a type of reactive oxygen species (ROS).

Physical Activity Can Produce Reactive Oxygen from an Electron Leak