Below normal leptin levels signal the brain to increase appetite so that body fat levels increase.

Question

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Leptin is a hormone produced by fat cells that helps to regulate body weight by signaling the brain to reduce appetite and burn more calories when body fat levels are sufficient. When leptin levels are below normal, it signals the brain that body fat levels are too low, leading to an increase in appetite to restore the body's fat stores.

Below Normal Leptin Levels Signal the Brain to Increase Appetite