One problem with producing biologics in cells that differ from human cells is that proteins may be alternately ___, which could affect purification and/or function of the ultimate pharmaceutical.

Question

Quizplus · Accepted Answer

All of the options listed (phosphorylated, glycosylated, cleaved, processed) represent potential modifications that can occur differently in non-human cells compared to human cells. These modifications can indeed affect both the purification process and the function of the biologic drugs produced, as they can alter the protein's structure, stability, and how it is recognized by the human body.

One Problem with Producing Biologics in Cells That Differ from Human