Which of the following explains why the aminoacyl-tRNA synthetase for isoleucine rarely incorporates valine despite the similar structure of these two amino acids?
A) valine does not fit into the binding site for isoleucine
B) only leucine and isoleucine can fit in the active site of the enzyme
C) before incorporation, the enzyme methylates valine to make it into an isoleucine
D) the enzyme contains a proofreading site that removes valine from the tRNA
E) none of the above
Correct Answer:
Verified
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