Diagnostic Specificity Is Defined as Which of the Following

Diagnostic specificity is defined as which of the following?

A) The probability that a laboratory test will be positive in the absence of disease
B) The probability that a laboratory test will be negative in the absence of disease
C) A measure of how often the assay system detects the biomarker when the disease is present
D) The probability that a disease is present when the test is positive or that a disease is absent when a test is negative