Plasma Clearance of a Drug Is Defined As

Plasma clearance of a drug is defined as:

A) The volume of plasma from which all drug appears to be removed in a given volume of blood (e.g., mL/mL) .
B) The volume of plasma from which all drug appears to be removed in a given time (e.g., mL/min) .
C) The amount of drug removed from urine in a given time (e.g., mg/min) .
D) The amount of time it takes for a drug to reach seven half-lives.