Elevated blood levels of pregnancy-associated plasma protein A (PAPP-A) may suggest which of the following?

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Pregnancy-associated plasma protein A (PAPP-A) is a protein that can be elevated in various conditions, including pregnancy and cardiovascular diseases. In the context of cardiovascular disease, elevated levels of PAPP-A have been associated with unstable angina and acute coronary syndromes (ACS) in patients who do not have elevated biomarkers of necrosis, such as cardiac troponins (cTn). This makes it a potential marker for identifying patients with unstable forms of ACS who might otherwise be missed using traditional biomarkers.

Elevated Blood Levels of Pregnancy-Associated Plasma Protein a (PAPP-A) May