A Home Health Nurse Is Making a Visit to a Family

A home health nurse is making a visit to a family with an 8-month-old infant with severe motor deterioration. The physician has diagnosed the infant with Tay-Sachs disease. The parents are asking the nurse why this happened. The nurse will base her answer knowing the root cause of Tay-Sachs is

A) high exposure to lead in the home environment.
B) an enzyme defect causing abnormal lipid accumulation in the brain.
C) hypoxia caused by placing the infant on their abdomen during sleep.
D) an increase in bilirubin retention leading to destruction of RBCs.