A 77-year-old female diagnosed with chronic obstructive pulmonary disease (COPD) is^{experiencing impaired gas exchange and CO}2 ^{retention, despite a rapid respiratory rate.} Which of the following pathophysiological principles would her health care team expect if her compensatory mechanisms are working?

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Quizplus · Accepted Answer

Respiratory acidosis is accompanied by renal adaptation with a more marked increase in plasma HCO ^-and a lesser decrease in pH. Her pH is likely below 7.35, and the likely renal response involves the reabsorption of HCO ^-and secretion of H⁺. Excess CO production is not a common manifestation of obstructive lung disease.

A 77-Year-Old Female Diagnosed with Chronic Obstructive Pulmonary Disease (COPD)