A 37-year-old male with HIV who has recently become symptomatic has begun highly active antiretroviral therapy (HAART). Among the numerous medications that the man now regularly takes are several that inhibit the change of HIV RNA to DNA in a CD4⁺ cell. Which of the following classes of medications addresses this component of the HIV replication cycle? A) Entry inhibitors B) Protease inhibitors C) Integrase inhibitors D) Non-nucleoside reverse transcriptase inhibitors

Question

Quizplus · Accepted Answer

Reverse transcriptase inhibitors inhibit HIV replication by acting on the enzyme reverse transcriptase. Non-nucleotide reverse transcriptase inhibitors block the copying of RNA into DNA. Entry inhibitors, protease inhibitors, and integrase inhibitors do not address this aspect of the HIV replication cycle.

A 37-Year-Old Male with HIV Who Has Recently Become Symptomatic