Misinterpreting her physician's instructions, a 69-year-old woman with a history of peripheral artery disease has been taking two 325 mg tablets of aspirin daily. How has this most likely affected her hemostatic status? A) Irreversible acetylation of platelet cyclooxygenase activity has occurred. B) ^{The patient's prostaglandin (TXA}2⁾^{levels are abnormally}^high. C) She is at risk of developing secondary immune thrombocytopenic purpura (ITP). D) The binding of an antibody to platelet factor IV produces immune complexes.

Question

Quizplus · Accepted Answer

Aspirin can cause inhibition of platelet aggregation that lasts for the life of the platelet. ^{High TXA}2 ^{levels would be associated with increased coagulability. I}^{TP would not}result from aspirin intake, and binding of an antibody to platelet factor IV is associated with heparin-induced thrombocytopenia.

Misinterpreting Her Physician's Instructions, a 69-Year-Old Woman with a History