A 60-year-old woman is suspected of having non-Hodgkin lymphoma (NHL). Which of the following aspects of her condition would help to rule out Hodgkin lymphoma?
A) Her neoplasm originates in secondary lymphoid structures.
B) The lymph nodes involved are located in a large number of locations in the lymphatic system.
C) The presence of Reed-Sternberg cells has been confirmed.
D) The woman complains of recent debilitating fatigue.

Question

Quizplus · Accepted Answer

While NHLs tend to be multicentric, Hodgkin lymphoma tends to involve a single node or group of nodes. The presence of Reed-Sternberg cells would indicate Hodgkin lymphoma, and both NHL and Hodgkin lymphoma involve secondary lymphoid structures and would cause fatigue.

A 60-Year-Old Woman Is Suspected of Having Non-Hodgkin Lymphoma (NHL)