Which of the following patients will likely experience difficulty in maintaining lipoprotein synthesis resulting in elevated LDL levels?
A) A 55-year-old male admitted for exacerbation of chronic obstructive pulmonary disease (COPD)
B) A 44-year-old female admitted for hysterectomy due to cervical cancer with metastasis
C) A 35-year-old patient with a history of hepatitis C and B with end-stage liver disease
D) A 27-year-old patient with pancreatitis related to alcohol abuse

Question

Quizplus · Accepted Answer

There are two sites of lipoprotein synthesis-the small intestine and the liver. The liver synthesizes and releases VLDL and HDL. IDL are taken to the liver and recycled to form VLDL or converted to LDL in the vascular compartment. Liver disease will result in this mechanism not working as expected. COPD, cervical cancer, and pancreatitis are not involved in elevated LDL levels.

Which of the Following Patients Will Likely Experience Difficulty in Maintaining