When explaining the role of the proximal tubule in terms of medication administration, the nursing instructor will emphasize that which of the following medications are bound to plasma proteins and require the proximal tubule secretion of exogenous organic compounds to help with filtration? Select all that apply.
A) Penicillin
B) Aspirin
C) Morphine sulfate
D) Potassium chloride
E) Sodium chloride

Question

Quizplus · Accepted Answer

The proximal tubule secretes exogenous organic compounds such as penicillin, aspirin, and morphine. Many of these compounds can be bound to plasma proteins and are not freely filtered in the glomerulus. Therefore, excretion by filtration alone eliminates only a small portion of these potentially toxic substances from the body.

When Explaining the Role of the Proximal Tubule in Terms