A 34-Year-Old Man Has Been Taking Up to 2400 Mg

A 34-year-old man has been taking up to 2400 mg of ibuprofen per day following a motor vehicle accident several months ago and consequent chronic pain. He has recently been diagnosed with chronic analgesic nephritis as a result of his high analgesic intake. The man is surprised at the diagnosis stating, "I thought that taking too many drugs hurts your liver if anything, not your kidneys." What is the most appropriate response to the man's statement?

A) "Your liver does perform most of the detoxification in your body, but your kidneys can perform this role if the liver is unable to."
B) "High drug intake can cause your kidneys to be very vulnerable to infections, which is likely what happened in your case."
C) "Your kidneys are vulnerable to damage because of how much blood flows through them and the fact that they break down many drugs."
D) "It is very rare for someone as young as yourself to have kidney damage like this; usually only older people are vulnerable to kidney damage from drugs."